The Mac and Cheese Meatloaf Casserole is a delightful fusion of two classic comfort foods: meatloaf and mac and cheese. This hearty dish combines flavorful meatloaf with creamy, cheesy macaroni, making it a perfect meal for family dinners and gatherings. It’s rich, satisfying, and sure to become a new favorite!
Ingredients:
- 1 cup ketchup
 - 1 cup Sweet Baby Ray’s Hickory & Brown Sugar barbecue sauce
 - 2 lbs lean ground beef
 - 30 Ritz Crackers, crushed
 - 2 oz Lipton onion soup mix
 - 2 eggs
 - 3 cups macaroni noodles
 - 2 cups milk
 - 10.5 oz condensed cheddar cheese soup
 - 1 tsp salt
 - 1 tsp pepper
 - 1 tbsp garlic powder
 - 1 tbsp onion powder
 - 4 cups shredded mozzarella and cheddar cheese blend
 
Instructions:
- Preheat the Oven:
 
- Preheat the oven to 350°F (175°C). Grease a 9×13 inch baking dish.
 
- Prepare the Sauce:
 
- In a medium mixing bowl, combine the ketchup and barbecue sauce. Set aside.
 
- Make the Meatloaf:
 
- In a large mixing bowl, add the ground beef. Crush the Ritz Crackers and add them to the bowl.
 - Add the Lipton onion soup mix and eggs. Pour in 1/2 cup of the ketchup and barbecue sauce mixture.
 - Mix all ingredients together until fully combined. Press the mixture evenly into the baking dish.
 - Spread the remaining ketchup and barbecue sauce mixture on top.
 - Bake for 30 minutes.
 
- Cook the Macaroni:
 
- Cook the macaroni noodles according to package directions, then drain.
 
- Prepare the Cheese Sauce:
 
- In a large bowl, whisk together milk and condensed cheddar cheese soup until smooth.
 - Add salt, pepper, garlic powder, and onion powder. Stir in the cooked macaroni and 2 cups of shredded cheese.
 
- Combine and Bake:
 
- Remove the meatloaf from the oven. Pour the macaroni mixture on top and spread evenly.
 - Sprinkle the remaining cheese on top.
 - Bake for an additional 17-20 minutes, until the cheese is melted and starting to brown.
 - Let sit for a few minutes before serving.
 
Helpful Tips:
- Cheese Blend: Customize the cheese blend to your preference. A mix of cheddar, mozzarella, and Monterey Jack works well.
 - Gluten-Free: For a gluten-free version, use gluten-free crackers, soup mix, and noodles.
 - Make-Ahead: This dish can be prepared ahead of time and baked just before serving.
 
Serving Suggestions:
- Serve with a side salad or steamed vegetables for a balanced meal.
 - Pair with garlic bread for an extra touch of indulgence.
 
FAQs:
- Can I use a different type of meat?
 
- Yes, you can use ground turkey or chicken for a leaner option.
 
- How do I store leftovers?
 
- Store any leftovers in an airtight container in the refrigerator for up to 3 days. Reheat in the oven or microwave before serving.
 
- Can I freeze this casserole?
 
- Yes, you can freeze the casserole. Wrap it tightly in foil and plastic wrap before freezing. Thaw in the refrigerator overnight before reheating.
 
- What other sauces can I use?
 
- If you prefer a different flavor, try using a different barbecue sauce or even a tomato-based sauce.
 
Total Time:
- Prep Time: 20 minutes
 - Cooking Time: 45 minutes (30 minutes for meatloaf + 15 minutes for macaroni)
 - Total Time: 1 hour 5 minutes
 
Nutrition:
- Calories: Approximately 600 kcal per serving
 - Yield: 8 servings
 
Enjoy this comforting Mac and Cheese Meatloaf Casserole, perfect for family dinners and gatherings!
Recipe Card

Mac and Cheese Meatloaf Casserole
The Mac and Cheese Meatloaf Casserole is a delightful fusion of two classic comfort foods: meatloaf and mac and cheese. This hearty dish combines flavorful meatloaf with creamy, cheesy macaroni, making it a perfect meal for family dinners and gatherings. It’s rich, satisfying, and sure to become a new favorite!
Ingredients
- – 1 cup ketchup
 - – 1 cup Sweet Baby Ray’s Hickory & Brown Sugar barbecue sauce
 - – 2 lbs lean ground beef
 - – 30 Ritz Crackers crushed
 - – 2 oz Lipton onion soup mix
 - – 2 eggs
 - – 3 cups macaroni noodles
 - – 2 cups milk
 - – 10.5 oz condensed cheddar cheese soup
 - – 1 tsp salt
 - – 1 tsp pepper
 - – 1 tbsp garlic powder
 - – 1 tbsp onion powder
 - – 4 cups shredded mozzarella and cheddar cheese blend
 
Instructions
Preheat the Oven:
- – Preheat the oven to 350°F (175°C). Grease a 9×13 inch baking dish.
 
Prepare the Sauce:
- – In a medium mixing bowl, combine the ketchup and barbecue sauce. Set aside.
 
Make the Meatloaf:
- – In a large mixing bowl, add the ground beef. Crush the Ritz Crackers and add them to the bowl.
 - – Add the Lipton onion soup mix and eggs. Pour in 1/2 cup of the ketchup and barbecue sauce mixture.
 - – Mix all ingredients together until fully combined. Press the mixture evenly into the baking dish.
 - – Spread the remaining ketchup and barbecue sauce mixture on top.
 - – Bake for 30 minutes.
 
Cook the Macaroni:
- – Cook the macaroni noodles according to package directions, then drain.
 
Prepare the Cheese Sauce:
- – In a large bowl, whisk together milk and condensed cheddar cheese soup until smooth.
 - – Add salt, pepper, garlic powder, and onion powder. Stir in the cooked macaroni and 2 cups of shredded cheese.
 
Combine and Bake:
- – Remove the meatloaf from the oven. Pour the macaroni mixture on top and spread evenly.
 - – Sprinkle the remaining cheese on top.
 - – Bake for an additional 17-20 minutes, until the cheese is melted and starting to brown.
 - – Let sit for a few minutes before serving.